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Antiemetics: Technologies and Global Markets

  • Published Date: 17 Jul 2018
  • Number of Pages: 115
  • Category: Pharmaceuticals
  • Country: Global
Summary

Emesis is a devastating adverse effect of surgery, poisoning, chemotherapy, vestibular imbalance, medication, radiotherapy and during pregnancy. Emesis itself is not a disease but an indication of a stressed physiological condition. During the last decades, extraordinary technological advances have made innovations in most of the disease therapies, including cancer therapies, which is the most common cause of emesis.

Antiemetic drug market is population driven and mostly depends on the number of chemotherapy and radiation therapy sessions performed in specific geographic regions that have high cancer burden and utilize chemotherapy and radiation therapy for cancer treatment. Antiemetics are used to suppress nausea and vomiting associated with CINV, PINV, NVP, RINV, motion sickness and vestibular sickness. 5-HT3 receptor antagonists and NK1 receptor antagonists are the most frequently used antiemetic drug categories.

The global market for antiemetics in 2017 was nearly REDACTED and is expected to reach REDACTED during the forecast period of 2018-2023. The 5-HT3 receptor antagonist market accounts for the largest market share (REDACTED) of the global antiemetic market. NK1 receptor antagonists are the second largest antiemetic drug segment. NK1 receptor antagonists antiemetic drug market is expected to increase at the rate of REDACTED CAGR, thanks to the approval of the U.S. Food and Drug Administration(FDA), commercial launch of new drug candidates, and the existing pipeline which is likely to hit the market in by 2023. Anticholinergics and benzodiazepines are the smallest antiemetic market segments, accounting for approximately REDACTED of the overall market share.

Based on applications CINV contribution to antiemetic drug was approximately REDACTED in 2017. Motion sickness and vestibular disorder is the second largest segment by application, accounting for approximately REDACTED in 2017. The CINV market is expected to rise by a CAGR REDACTED during the forecast period. North America is the leading contributor to antiemetic drug market, accounting for about REDACTED of the antiemetic drug market. Middle East and Africa antiemetic market is expected to grow at the highest rate (REDACTED CAGR) during the forecast period.
Publisher Name : BCC Research

Chapter 1 Introduction
Antiemetic Technologies
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analysts Credentials
Related BCC Research Reports
Chapter 2 Summary and Highlights
Chapter 3 Overview
Introduction
Causes of Nausea and Vomiting
Gastrointestinal Obstruction/Infection/Inflammation
Drug-Induced Nausea and Vomiting
Pregnancy-Induced Nausea and Vomiting
Post-operative Nausea and Vomiting
Vestibular Disorder
Pathophysiology of Nausea and Vomiting
Gastrointestinal Tract
Chemoreceptor Trigger Zone
Vestibular Apparatus
Cerebral Cortex
Chapter 4 Market and Technology Background
Drivers
Global Increase in Number of Pregnancies and Burden of Underlying Disease Conditions
Increasing in Research Grants and Funding
Growing Research Activity in Innovative Antiemetic Drug Therapy
Use of Novel Drug Deliveries to Treat Nausea and Vomiting
Restraints
Lack of Animal Models to Prove Efficacy of Antiemetics
Pricing Pressure Experienced by Innovators
Availability of Alternative Treatments
Opportunities
Disease Burden and Increasing Number of Pregnancies in Europe and Asia-Pacific
Vestibular Disorders
Emergence of Advanced Therapies
Patent Expiry
Chapter 5 Market Breakdown by Drug Class
Introduction
Global Antiemetic Drugs Market
5-HT3 Receptor Antagonists
NK1 Receptor Antagonist
Dopamine Antagonists
Antihistamines (H1 Receptor Antagonists)
Cannabinoids
Benzodiazepines
Corticosteroids
Anticholinergics
Chapter 6 Market Breakdown by Application
Overview
Market Size and Forecast
Chemotherapy-Induced Nausea and Vomiting
Introduction
Market Size and Forecast
Key CINV Market Takeaways
Gastroenteritis
Market Size and Forecast
Nausea and Vomiting of Pregnancy (NVP)
Market Size and Forecast
Post-Operative Nausea and Vomiting
Market Size and Forecast
Chapter 7 Market Breakdown by Region
Overview
Market Size and Forecast
North America
Market Size and Forecast
United States
Canada
Mexico
Europe
Market Size and Forecast
United Kingdom
Germany
Asia-Pacific
Market Size and Forecast
Middle East and Africa
South America
Chapter 8 Patent Review/New Developments
Introduction
Chapter 9 Pipeline Analysis
Introduction
NK1 Receptor Antagonists
Chapter 10 Regulatory Landscape
Introduction
Regional Regulatory Landscape
North America
Europe
Asia-Pacific
Chapter 11 Company Profiles
ABBOTT LABORATORIES
Overview
Financial Information
Products and Services
Development and Strategies
ASTELLAS PHARMA INC.
Overview
Financial Information
Products and Services
Development and Strategies
APHIOS CORP.
Overview
AUROBINDO PHARMA
Overview
Financial Information
Products and Services
DAIICHI SANKYO COMPANY LTD.
Overview
Financial Information
Product and Services
Development and Strategies
EISAI CO., INC.
Overview
Financial Information
Products and Services
GLAXOSMITHKLINE PLC
Overview
Financial Information
Products and Services
HELSINN HEALTHCARE SA
Overview
Products and Services
Key Developments and Strategies
HERON THERAPEUTICS, INC.
Overview
Financials
Products and Services
IPCA LABORATORIES, LTD.
Overview
KYOWA HAKKO KIRIN PHARMA, INC.
Overview
Financials
MERCK & CO., INC.
Overview
Financial Information
Products and Services
NOVARTIS AG
Overview
Financial Information
F. HOFFMANN-LA ROCHE AG
Overview
Financial Information
Products and Services
SANOFI AVENTIS
Overview
Financial Information
Products and Services
TESARO, INC.
Overview
Financial Information
Products and Services
Development and strategies
TEVA PHARMACEUTICAL INDUSTRIES LTD.
Overview
Financial Information
Product and Services
Development and Strategies
Chapter 12 Appendix: Abbreviations

List Of Tables

List of Tables
Summary Table A : Global Antiemetic Drugs Market, by Drug Class, Through 2023
Summary Table B : Global Antiemetic Drugs Market, by Application, Through 2023
Table 1 : Emetic Potency of Chemotherapeutic Agents
Table 2 : Vomiting as Adverse Effect at Therapeutic Dosage
Table 3 : Ondansetron Patent Expiration
Table 4 : Aloxi Patent Expiration
Table 5 : List of FDA approved Antiemetic Drugs and Indications
Table 6 : Global Antiemetic Drugs Market, by Drug Class, Through 2023
Table 7 : 5-HT3 Receptor Drugs
Table 8 : FDA Approved Dopamine Antagonists
Table 9 : Global Antiemetic Drugs Market, by Application, Through 2023
Table 10 : Global Antiemetic Drugs Market, by Region, Through 2023
Table 11 : Antiemetic Drug Patents
Table 12 : Antiemetic Drug Candidates
Table 13 : FDA Approved Drugs
Table 14 : List of Antiemetic Drugs Approved in Japan
Table 15 : Abbott Laboratories: Net Revenue, 2015-2017
Table 16 : Abbott Laboratories: Net Revenue, by Segment, 2017
Table 17 : Abbott Laboratories: Marketed Products, 2016
Table 18 : Astellas Pharma Inc.: Net Revenue, 2015-2017
Table 19 : Astellas Pharma Inc.: Marketed Products, 2016
Table 20 : Aurobindo Pharma Ltd.: Net Revenue, 2015-2017
Table 21 : Daiichi Sankyo Company Ltd.: Net Revenue, 2015-2017
Table 22 : Eisai Co., Inc.: Net Revenue, by Region, 2014-2016
Table 23 : Eisai Co., Inc.: Oncology Product Sales, 2014-2016
Table 24 : GlaxoSmithKline PLC: Net Revenue, 2014-2016
Table 25 : Heron Therapeutics Inc.: Net Revenue, 2016-2017
Table 26 : Kyowa Hakko Kirin Pharma Inc.: Net Revenue, 2013-2017
Table 27 : Merck & Co. Inc.: Net Revenue, 2014-2016
Table 28 : Novartis AG: Net Revenue, 2014-2016
Table 29 : F. Hoffmann-La Roche Ltd.: Net Revenue, by Segment, Through 2017
Table 30 : Sanofi: Net Revenue, 2014-2016
Table 31 : Teva Pharmaceutical Industries Ltd.: Net Revenue, 2015-2017
Table 32 : Teva Pharmaceutical Industries Ltd.: Net Revenue, by Segments, 2015-2017
Table 33 : Teva Pharmaceutical Industries Ltd: Products and Services
Table 34 : Abbreviations

List Of Figures

List of Figures
Summary Figure A : Global Antiemetic Drugs Market, by Drug Class, 2017-2023
Summary Figure B : Global Antiemetic Drugs Market, by Application, 2017-2023
Figure 1 : Mechanism of Chemotherapy-Induced Nausea and Vomiting
Figure 2 : Pathophysiology of Nausea and Vomiting
Figure 3 : Pathophysiology of Emesis
Figure 4 : Global Antiemetic Drugs Market, by Drug Class, 2017-2023
Figure 5 : Global Market Share of Antiemetics, by Drug Class, 2017
Figure 6 : Global 5-HT3 Receptor Market, 2017-2023
Figure 7 : Global NK1 Receptor Antagonist Market, 2017-2023
Figure 8 : Global Dopamine Receptor Market, 2017-2023
Figure 9 : Global Antihistamines Receptor Antagonist Market, 2017-2023
Figure 10 : Global Cannabinoids Market, 2017-2023
Figure 11 : Global Benzodiazepines Market, 2017-2023
Figure 12 : Global Corticosteroid Market, 2017-2023
Figure 13 : Global Anticholinergic Drugs Market, 2017-2023
Figure 14 : Global Market Share for Antiemetics Drug, by Application, 2017
Figure 15 : Global CINV Drugs Market, 2017-2023
Figure 16 : Global Gastroenteritis Antiemetic Drug Market, 2017-2023
Figure 17 : Global NVP Antiemetic Drug Market, 2017-2023
Figure 18 : Global PONV Antiemetic Drugs Market, 2017-2023
Figure 19 : Global Antiemetic Drugs Market, by Region, 2017-2023
Figure 20 : North America Antiemetic Drugs Market, 2017-2023
Figure 21 : North America Antiemetic Drugs Market, by Application, 2017-2023
Figure 22 : Europe Antiemetic Drugs Market, 2017-2023
Figure 23 : Europe Antiemetic Drugs Market, by Application, 2017-2023
Figure 24 : Asia-Pacific Antiemetic Drugs Market, 2017-2023
Figure 25 : Asia-Pacific Antiemetic Drugs Market, by Application, 2017-2023
Figure 26 : Middle East and Africa Antiemetic Drugs Market, 2017-2023
Figure 27 : South America Antiemetic Drugs Market, 2017-2023
Figure 28 : Abbott Laboratories: Revenue Share, by Segment, 2017
Figure 29 : Astellas Pharma Inc.: Revenue Share, by Segment, 2017
Figure 30 : Aurobindo Pharma Ltd.: Revenue Share, by Segment, 2017
Figure 31 : Daiichi Sankyo Company Ltd.: Revenue Share, by Business Segment, 2016
Figure 32 : GlaxoSmithKline PLC: Revenue Share, by Business Segment, 2016
Figure 33 : GlaxoSmithKline PLC: Revenue Share, by Region, 2016
Figure 34 : Merck & Co. Inc.: Revenue Share, by Business Segment, 2016
Figure 35 : Merck & Co. Inc.: Revenue Share, by Region, 2016
Figure 36 : Novartis AG: Revenue Share, by Region, 2016
Figure 37 : Novartis AG: Revenue Share, by Business Segment, 2016
Figure 38 : F. Hoffmann-La Roche Ltd.: Pharmaceuticals Revenue Share, by Business Segment, 2016
Figure 39 : Sanofi: Revenue Share, by Region, 2016
Figure 40 : Sanofi: Revenue Share, by Business Segment, 2016
Figure 41 : Sanofi: Revenue Share, by Pharmaceuticals Segment, 2017
Figure 42 : Tesaro, Inc.: Net Revenue, 2015-2017
Figure 43 : Teva Pharmaceutical Industries Ltd.: Generic Medicines Segment Revenue Share, by Region, 2017

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