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Global Genome Editing Market Forecast to 2025

  • Published Date: 27 Feb 2019
  • Number of Pages: 97
  • Category: Healthcare and Medical
  • Country: Global

Global Genome Editing Market - Drivers, Restraints, Opportunities, Trends, and Forecast, 2019–2025

This market research report includes a detailed segmentation of the global genome editing market – by technology (CRISPR, TALEN, ZFN, and Others), by application (Cell Line Engineering, Genetic Engineering, and Others), By end-user (Research Institutes, Biotechnology and Pharmaceutical Companies, and Contract Research Organizations), by regions (North America, Europe, Asia Pacific, and Rest of the World).
Overview of the Global Genome Editing Market


Our market research report predicts that the “Global Genome Editing Market” will grow at a CAGR of 14.4% during the forecast period. The market has witnessed steady growth in the past few years with the development in technology and the introduction of highly sensitive, robust, and reliable systems in the market. The market is fueled due to increase in genetic disorders, increasing investment and funds, and technological advancements in genome editing.


The market continues to grow and is one of the increasingly accepted market in many countries worldwide. Vendors are focusing towards obtaining funds and collaborating with universities to enlarge their research and development capabilities. The majority of the revenue is generated from the leading players in the market with dominating sales of ThermoFisher Scientific, GenScript Corp., Sangamo Therapeutics, Lonza Group, and Horizon Discovery Group plc.


According to Research analysis, North America accounted for the largest share of the global genome editing market in 2018. US dominates the market with majority of genome editing companies being located in this region. However, China has not been too far behind and has great government support for the research in genome editing field.  


By Technology:


• CRISPR
• TALEN
• ZFN
• Others


In 2018, the CRISPR segment occupied the largest share due to specific, effective, and cost-effective nature of the technology. Many companies are focusing on providing genome editing services. For instance, in January 2019, Horizon Discovery extended CRISPR screening service to primary human T cells.


By Applications:


• Cell Line Engineering
• Genetic Engineering
• Others


In 2018, the cell line engineering accounted the maximum share followed by genetic engineering. Increase in the number of people suffering with genetic disorders has driven the growth of the genome editing market.


By End Users:

• Research Institutes
• Biotechnology and Pharmaceutical Companies
• Contract Research Organizations
In 2018, the biotechnology and pharmaceutical companies gained the highest market share for genome editing market due to increased pervasiveness of cancer and infectious diseases are driving research goings-on in biotechnology & pharmaceutical companies segment.


By Regions:
• North America
• Europe
• APAC
• ROW


The market is dominated by North America, followed by Asia Pacific and Europe. The major share of the North America market is from the US due to quick adoption of new and advanced technologies.


Genome Editing Market Research Competitive Analysis – The market is extremely fragmented with several smaller companies struggling for market share. Big pharmaceutical establishments have also united with venture capitalists to provide funding to the start-ups. In 2015, Bayer financed $335 million and in the very same year, Celgene combined with Abingworth invested $64 million in CRISPR Therapeutics. The NIH recently granted 21 somatic cell genome editing grants of almost $86 million over the next half a decade. These endowments are the foremost to be granted through the Somatic Cell Genome Editing (SCGE) program that was initiated in January 2018 with NIH Common Fund.


The companies are collaborating and licensing to increase their capabilities in the market. CRISPR, TALEN, ZFN, Meganuclease, ARCUS, and RTDS are some of the key technology areas concentrated by key players in the market. Since 2015, the deals on the CRISPR technology has drastically increased.


Key vendors:
• ThermoFisher Scientific
• GenScript Corp.
• Sangamo Therapeutics
• Lonza Group
• Horizon Discovery Group plc
• Merck KGaA
• Transposagen Biopharmaceutical
• CRISPR Therapeutics
• Editas Medicine
• Integrated DNA Technologies
• New England Biolabs
• Origene Technologies, Inc.


Key competitive facts –
• Genetic editing technologies are intensely evolving from previous two decades and has facilitated in the variation of genome further rapidly and in a less expensive technique.
• The US is the leader in the CRISPR technology, while the market for TALEN genome editing technology is dominated by China.
Benefits – The report provides complete details about the usage and adoption rate of genome editing market. Thus, the key stakeholders can know about the major trends, drivers, investments, vertical player’s initiatives, and government initiatives towards the healthcare segment in the upcoming years along with details of the pureplay companies entering the market. Moreover, the report provides details about the major challenges that are going to impact the market growth. Additionally, the report gives complete details about the key business opportunities to key stakeholders in order to expand their business and capture the revenue in specific verticals, and to analyze before investing or expanding the business in this market.


Key Takeaways:
• Understanding the potential market opportunity with precise market size and forecast data
• Detailed market analysis focusing on the growth of genome editing industry
• Factors influencing the growth of genome editing market
• In-depth competitive analysis of dominant and pureplay vendors
• Prediction analysis of genome editing market in both developed and developing regions
• Key insights related to major segments of the genome editing market
• Latest market trend analysis impacting the buying behavior of the consumers

Publisher Name : Infoholic Research


1 Industry Outlook 9
1.1 Industry Overview 9
1.2 Total Addressable Market 9
1.2.1 Industry Trends 10


2 Report Outline 11
2.1 Report Scope 11
2.2 Report Summary 11
2.3 Research Methodology 13
2.4 Report Assumptions 13


3 Market Snapshot 14
3.1 Market Definition – Infoholic Research 14
3.2 Segmented Addressable Market (SAM) 14
3.3 Industry Trends 15
3.4 Related Markets 16
3.4.1 Genetic Testing 16
3.4.1.1 Trends of the genetic testing market 16
3.4.2 Liquid Biopsy Market 16
3.4.2.1 Trends of Liquid biopsy market 17
3.4.3 Next-generation sequencing 18
3.4.3.1 Trends in the Next-generation sequencing market 18


4 Market Outlook 19
4.1 Funding Scenario 19
4.2 International Patent Classification (IPC) Codes and for the Technology Areas 20
4.2.1 Life Science Research 20
4.2.2 General Research 21
4.3 Deals 21
4.4 Porter 5 (Five) Forces 26


5 Market Characteristics 28
5.1 Evolution 28
5.2 Market Segmentation 29
5.3 Market Dynamics 30
5.3.1 Drivers 30
5.3.1.1 Increase in Genetic Disorders 30
5.3.1.2 Increasing Investment and Funds 31
5.3.1.3 Technological Advancements in Genome Editing 31
5.3.2 Restraints 31
5.3.2.1 Ethical Concerns Associated to Genetic Editing 31
5.3.2.2 High Cost of Genome Engineering Technologies 32
5.3.3 Opportunities 32
5.3.3.1 Market Expansion Opportunities in Emerging Nations 32
5.3.3.2 Growing Collaboration for Genome Engineering Technologies 32
5.3.4 DRO – Impact Analysis 33
5.4 Key Stakeholders 34


6 Technology Types: Market Size and Analysis 35
6.1 Overview 35
6.2 CRISPR/Clustered Regularly Interspaced Short Palindromic Repeats 36
6.3 TALEN/Transcription Activator-Like Effector Nuclease 39
6.4 ZFN/Zinc-Finger Nucleases 40
6.5 Others 41


7 Application Types: Market Size and Analysis 43
7.1 Overview 43
7.2 Cell Line Engineering 44
7.3 Genetic Engineering 45
7.4 Others 48


8 End Users: Market Size and Analysis 50
8.1 Overview 50
8.2 Research Institutes 50
8.3 Biotechnology and Pharmaceutical Companies 51
8.4 Contract Research Organizations 52


9 Regions: Market Size and Analysis 53
9.1 Overview 53
9.2 North America 54
9.2.1 Overview 54
9.3 Europe 55
9.3.1 Overview 55
9.4 Asia Pacific 56
9.4.1 Overview 56
9.5 Rest of the World 57
9.5.1 Overview 57


10 Competitive Landscape 59


11 Vendors Profile 64
11.1 ThermoFisher Scientific, Inc. 64
11.1.1 Overview 64
11.1.2 Business Units 66
11.1.3 Geographic Presence 67
11.1.4 Business Focus 68
11.1.5 SWOT Analysis 68
11.1.6 Business Strategy 69
11.2 GenScript Corp. 70
11.2.1 Overview 70
11.2.2 Business Units 71
11.2.3 Geographic Presence 72
11.2.4 Business Focus 73
11.2.5 SWOT Analysis 73
11.2.6 Business Strategies 74
11.3 SANGAMO THERAPEUTICS, INC. 74
11.3.1 Overview 74
11.3.2 Business Focus 76
11.3.3 SWOT Analysis 77
11.3.4 Business Strategies 77
11.4 Lonza Group 78
11.4.1 Overview 78
11.4.2 Business Units 79
11.4.3 Geographic Presence 80
11.4.4 Business Focus 81
11.4.5 SWOT Analysis 81
11.4.6 Business Strategies 82
11.5 Horizon Discovery Group plc 82
11.5.1 Overview 82
11.5.2 Business Units 85
11.5.3 Geographic Presence 86
11.5.4 Business Focus 87
11.5.5 SWOT Analysis 87
11.5.6 Business Strategies 88


12 Companies to Watch for 89
12.1 Merck KGaA 89
12.1.1 Overview 89
12.2 Transposagen Biopharmaceuticals 90
12.2.1 Overview 90
12.3 CRISPR Therapeutics 91
12.3.1 Overview 91
12.4 Editas Medicine 92
12.4.1 Overview 92
12.5 Integrated DNA Technologies 93
12.5.1 Overview 93
12.6 New England Biolabs 94
12.6.1 Overview 94
12.7 Origene Technologies, Inc. 95
12.7.1 Overview 95


Annexure 97
Acronyms 97



List Of Tables

Tables

TABLE 1 DEALS BETWEEN 2011–2016 23
TABLE 2 GENOME EDITING MARKET REVENUE, BY TECHNOLOGY TYPE, 2018–2025 ($MILLION) 37
TABLE 3 GENOME EDITING MARKET REVENUE, BY APPLICATION TYPE, 2018-2025 ($MILLION) 44
TABLE 4 GENOME EDITING MARKET REVENUE, BY PRODUCT TYPE, 2018–2025 ($MILLION) 55
TABLE 5 COST COMPARISION OF GENOME EDITING TECHNOLOGY 60
TABLE 6 KEY DEVELOPMENTS IN THE MARKET 61
TABLE 7 THERMO FISHER SCIENTIFIC: PRODUCT OFFERINGS 65
TABLE 8 THERMO FISHER SCIENTIFIC: RECENT DEVELOPMENTS 66
TABLE 9 GENSCRIPT CORPORATION: PRODUCT OFFERINGS 71
TABLE 10 GENSCRIPT CORPORATION: RECENT DEVELOPMENTS 71
TABLE 11 SANGAMO THERAPEUTICS, INC.: PRODUCT OFFERINGS 76
TABLE 12 SANGAMO THERAPEUTICS, INC.: RECENT DEVELOPMENTS 76
TABLE 13 LONZA GROUP: OFFERINGS 79
TABLE 14 LONZA GROUP: RECENT DEVELOPMENTS 79
TABLE 15 HORIZON DISCOVERY GROUP PLC: OFFERINGS 84
TABLE 16 HORIZON DISCOVERY GROUP PLC: RECENT DEVELOPMENTS 84
TABLE 17 MERCK KGAA: SNAPSHOT 90
TABLE 18 MERCK KGAA: RECENT DEVELOPMENTS 90
TABLE 19 TRANSPOSAGEN BIOPHARMACEUTICALS: SNAPSHOT 91
TABLE 20 TRANSPOSAGEN BIOPHARMACEUTICALS: RECENT DEVELOPMENTS 91
TABLE 21 CRISPR THERAPEUTICS: OVERVIEW 92
TABLE 22 CRISPR THERAPEUTICS: RECENT DEVELOPMENTS 92
TABLE 23 EDITAS MEDICINE: OVERVIEW 93
TABLE 24 EDITAS MEDICINE: RECENT DEVELOPMENTS 93
TABLE 25 INTEGRATED DNA TECHNOLOGIES: SNAPSHOT 94
TABLE 26 INTEGRATED DNA TECHNOLOGIES: RECENT DEVELOPMENTS 94
TABLE 27 NEW ENGLAND BIOLABS: OVERVIEW 95
TABLE 28 NEW ENGLAND BIOLABS: RECENT DEVELOPMENTS 95
TABLE 29 ORIGENE TECHNOLOGIES, INC.: OVERVIEW 96
TABLE 30 ORIGENE TECHNOLOGIES, INC.: RECENT DEVELOPMENTS 96



List Of Figures

Charts

CHART 1 RESEARCH METHODOLOGY OF GLOBAL GENOME EDITING MARKET 13
CHART 2 GLOBAL GENOME EDITING MARKET REVENUE, 2018–2025 ($MILLION) 16
CHART 3 PORTERS 5 FORCES ON GLOBAL GENOME EDITING MARKET 27
CHART 5 GLOBAL GENOME EDITING MARKET SEGMENTATION 30
CHART 6 MARKET DYNAMICS – DRIVERS, RESTRAINTS & OPPORTUNITIES 31
CHART 7 DRO - IMPACT ANALYSIS OF GLOBAL GENOME EDITING MARKET 34
CHART 8 KEY STAKEHOLDERS OF GENOME EDITING MARKET 35
CHART 9 GENOME EDITING MARKET SEGMENT REVENUE BY TECHNOLOGY TYPE, 2018 VS 2025 ($MILLION) 37
CHART 10 CRISPR GENOME EDITING MARKET REVENUE 2018–2025 ($MILLION) 39
CHART 11 CRISPR GENOME EDITING MARKET REVENUE, BY REGION 2018 (%SHARE) 39
CHART 12 TALEN GENOME EDITING MARKET REVENUE 2018–2025 ($MILLION) 40
CHART 13 ZFN GENOME EDITING MARKET REVENUE 2018–2025 ($MILLION) 42
CHART 14 OTHER GENOME EDITING MARKET REVENUE 2018–2025 ($MILLION) 43
CHART 15 GENOME EDITING MARKET SEGMENT REVENUE. BY APPLICATION TYPE, 2018 VS 2025 ($MILLION) 44
CHART 16 CELL LINE ENGINEERING MARKET REVENUE 2018–2025 ($MILLION) 46
CHART 17 GENETIC ENGINEERING MARKET REVENUE 2018–2025 ($MILLION) 48
CHART 18 GENETIC ENGINEERING MARKET REVENUE, BY APPLICATION TYPES, 2018–2025 ($MILLION) 48
CHART 19 OTHER GENOME EDITING MARKET REVENUE 2018–2025 ($MILLION) 50
CHART 20 GENOME EDITING MARKET SEGMENT REVENUE BY END USERS, 2018 (%) 51
CHART 21 TOP PUBLISHING ORGANIZATIONS FOR RESEARCH IN LIFE SCIENCE GENOME EDITING 52
CHART 22 GENOME EDITING MARKET BY REGIONAL SEGMENTATION, 2018 VS 2025 ($MILLION) 54
CHART 23 GENOME EDITING MARKET REVENUE IN NORTH AMERICA, 2018–2025 ($MILLION) 56
CHART 24 GENOME EDITING MARKET REVENUE IN EUROPE 2018–2025 ($MILLION) 57
CHART 25 GENOME EDITING MARKET REVENUE IN ASIA PACIFIC, 2018–2025 ($MILLION) 58
CHART 26 GENOME EDITING REVENUE IN REST OF THE WORLD, 2018–2025 ($MILLION) 59
CHART 27 THERMO FISHER SCIENTIFIC: OVERVIEW SNAPSHOT 66
CHART 28 THERMO FISHER SCIENTIFIC: BUSINESS UNITS 67
CHART 29 THERMO FISHER SCIENTIFIC: GEOGRAPHIC PRESENCE 68
CHART 30 THERMO FISHER SCIENTIFIC: SWOT ANALYSIS 69
CHART 31 GENSCRIPT CORPORATION: OVERVIEW SNAPSHOT 71
CHART 32 GENSCRIPT CORPORATION: BUSINESS UNITS 72
CHART 33 GENSCRIPT CORP.: GEOGRAPHIC PRESENCE 73
CHART 34 GENSCRIPT CORPORATION: SWOT ANALYSIS 74
CHART 35 SANGAMO THERAPEUTICS, INC.: OVERVIEW SNAPSHOT 76
CHART 36 SANGAMO THERAPEUTICS, INC.: SWOT ANALYSIS 78
CHART 37 LONZA GROUP: OVERVIEW SNAPSHOT 79
CHART 38 LONZA GROUP: BUSINESS UNITS 80
CHART 39 LONZA GROUP: GEOGRAPHIC PRESENCE 81
CHART 40 LONZA GROUP: SWOT ANALYSIS 82
CHART 41 HORIZON DISCOVERY GROUP PLC: OVERVIEW SNAPSHOT 85
CHART 42 HORIZON DISCOVERY GROUP PLC: BUSINESS UNITS 86
CHART 43 HORIZON DISCOVERY GROUP PLC: GEOGRAPHIC PRESENCE 87
CHART 44 HORIZON DISCOVERY GROUP PLC: SWOT ANALYSIS 88



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